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One of the pathognomonic COVID19 signs, occurring in 8598% of patients, is olfactory dysfunction, developing in the absence of pronounced nflammation and edema of the nasal mucosa. A promising medicine direction that helps restore microcirculation, increase blood oxygenation, improve metabolism and regenerate olfactory epithelial cells is the Nadi Shodhana breathing exercise technique. Objective: To assess the possibilities of using the pranayama technique as a method of restorative olfactory treatment in the postcovid period. Materials and methods: 79 persons aged 22 to 68 years with olfactory disturbances occurring at COVID19 and persisting in the postcovid period were examined. As a restorative treatment for olfactory disorders, the patients of the main group were offered a course of Nadi Shodhana breathing xercises, which is an alternate nostril breathing. Breathing training consisted of three such cycles performed three times a day at the same time for 5 days. The possibility of using the pranayama technique was assessed according to the visual analog scale. The control group consisted of 74 patients with olfactory disorders after COVID19 comparable in sex and age with the main group. Results: Olfactory disorders are characteristic of postCOVID patients. Using Nadi Shodhana breathing exercise course can significantly reduce the lfactory dysfunction level in this patient category. It was showen that the pranayama technique is more effective in people under 40 years of age. It was lso established that the olfaction restoration largely depends on the duration of the dysfunction period. Conclusion: The study results make it possible to recommend the using breathing exercises in patients underwent COVID19 to restore olfaction n the postCOVID period. Copyright: © 2018 Zhao Qi et al.
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The analysis of a clinical case with osteonecrosis of the maxillofacial region, which was a manifestation of a complication of a COVID-19 coronavirus infection, to show the diagnostic capabilities of computed tomography followed by multiplanar and 3D reconstructions. Materials and methods. Clinical observation of patient R. 53 years old is presented, with complaints of pain, painful swelling of the soft tissues of the right suborbital area, painfulness during chewing, which appeared in the early period after COVID-19. The patient was referred to the Department of Oral and Maxillofacial Surgery where she underwent comprehensive radiological examination to determine the nature of the changes and comprehensive treatment. Results. The diagnosis of osteonecrosis with the progression to the soft tissue suppuration and upper jaw destruction was verified by CT scan and confirmed by surgical intervention. Detection and detailed diagnosis of these changes was facilitated by multispiral computed tomography and 3D reconstructions during the follow-up. Discussion. COVID-19 coronavirus infection can be complicated by necrosis of the skeletal bones, including the jaw, which can be diagnosed with radiology methods. Various radiological methods can be used to diagnose this pathology, but CT scan of the maxillofacial region is the most informative. Conclusion. CT of the skull bones and facial skeleton in patients with osteonecrosis of the maxillofacial region provides complete diagnostic information about the localization and distribution of the lesion, which determines the further tactics of patient management taking into account the detected changes. As a result, timely initiated adequate treatment helped to cope with the progressing protracted pathological process of the maxillofacial region, which was a manifestation of a complication of the recent COVID-19 coronavirus infection. © 2022 Russian Electronic Journal of Radiology. All rights reserved.
RESUMEN
The analysis of a clinical case with osteonecrosis of the maxillofacial region, which was a manifestation of a complication of a COVID-19 coronavirus infection, to show the diagnostic capabilities of computed tomography followed by multiplanar and 3D reconstructions. Materials and methods. Clinical observation of patient R. 53 years old is presented, with complaints of pain, painful swelling of the soft tissues of the right suborbital area, painfulness during chewing, which appeared in the early period after COVID-19. The patient was referred to the Department of Oral and Maxillofacial Surgery where she underwent comprehensive radiological examination to determine the nature of the changes and comprehensive treatment. Results. The diagnosis of osteonecrosis with the progression to the soft tissue suppuration and upper jaw destruction was verified by CT scan and confirmed by surgical intervention. Detection and detailed diagnosis of these changes was facilitated by multispiral computed tomography and 3D reconstructions during the follow-up. Discussion. COVID-19 coronavirus infection can be complicated by necrosis of the skeletal bones, including the jaw, which can be diagnosed with radiology methods. Various radiological methods can be used to diagnose this pathology, but CT scan of the maxillofacial region is the most informative. Conclusion. CT of the skull bones and facial skeleton in patients with osteonecrosis of the maxillofacial region provides complete diagnostic information about the localization and distribution of the lesion, which determines the further tactics of patient management taking into account the detected changes. As a result, timely initiated adequate treatment helped to cope with the progressing protracted pathological process of the maxillofacial region, which was a manifestation of a complication of the recent COVID-19 coronavirus infection.Copyright © 2022 Russian Electronic Journal of Radiology. All rights reserved.
RESUMEN
A multidisciplinary approach in the treatment of COVID-19 warrants close attention to the role of the intestinal microbiome in terms of disease pathology, disruption of local and systemic homeostasis, and possible treatment strategies. Dysbiotic disorders affect the immune system on the level of postvaccination immunity, influencing the likelihood and severity of SARS-CoV-2 infection, indicating the importance of intestinal microbiota in the prevention of complications and risk reduction. The fundamental factor in the stability of the intestinal microflora is a diet that includes regular consumption of probiotic foods, which support healthy microbiota. Restoration of damaged intestinal microbiota in cases of dysbiosis requires specific supplements and foods, which vary significantly for each symbiont. In clinical practice, the most appropriate approach is a differentiated one, taking into account the severity of the dysbiotic condition, comorbidities, and the age of the patients. A bacteria consortium of the human microbiome is the basis for a bioprobiotics complex with targeted action. The translational benefits of such therapy in most common COVID-19 syndromes are in detail presented in this chapter. We discuss the role of SARS-CoV-2 infection on the microbiota, as well as pathogenetic mechanisms of microbiota disruption, local and systemic influencing factors, and treatment strategies. © 2023 Elsevier Inc. All rights reserved.
RESUMEN
Healthcare workers are one of the main risk groups for COVID-19 infection and should be provided priority protection. Objective. To examine the development dynamics and epidemic process manifestations of COVID-19 in healthcare workers as well as to assess the efficacy of intranasal human recombinant interferon alpha-2b (Grippferon®) for emergency medication-assisted nonspecific prevention of novel coronavirus infection. Patients and methods. The incidence of COVID-19 in Perm healthcare workers was examined using official statistical data in the epidemic dynamics. The prophylactic efficacy of Grippferon® was assessed in the analytic cohort prospective study, involving 561 healthcare workers of infectious diseases hospital departments. Results. The incidence rate of COVID-19 among healthcare workers in Perm for the examined period from 09.03.2020 to 06.12.2020 was four times higher, than in the general population. Healthcare workers aged 30–59 years were found to be more likely to develop COVID-19. Physicians had the highest risk of infection compared to other medical professionals. The pro phy lactic efficacy of Grippferon® was shown to be high in physicians and nurses, who were in contact with COVID-19 patients. Conclusion. Recombinant interferon alpha-2b-based medication Grippferon® can be recommended for emergency prevention of novel coronavirus infection to ensure epidemiological safety of healthcare workers and patients during the COVID-19 pandemic.